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If you’re looking to shed a few pounds, you might be tempted to try out popular new approaches like the keto diet or fasting. But you might be unwittingly worsening a problem you don’t even know you have: a fatty liver. Doctors are worried about an increasingly common condition called nonalcoholic fatty liver disease, or NAFLD, in which extra fat builds up in the liver. It may lead to serious consequences like cirrhosis and liver cancer —just like liver problems caused by drinking too much alcohol. A quarter of the global population is estimated to have NAFLD—which doctors pronounce as “nah-fold” or “naffle-dee. The liver disease affects about 35 percent of Americans. Scientists also believe the condition is linked to increased risk of liver cancer even in the absence of clear-cut cirrhosis, Rosen said. He has seen preliminary results from a Mayo Clinic study that suggest NAFLD can increase susceptibility to other forms of cancer as well.